Human chorionic gonadotrophin in CSF, not serum, predicts outcome in germinoma
نویسندگان
چکیده
منابع مشابه
Human chorionic gonadotrophin in CSF, not serum, predicts outcome in germinoma.
OBJECTIVES Some intracranial germinomas, which may contain syncytiotrophoblastic giant cells (STGCs), are associated with a mildly to moderately increased human chorionic gonadotropin (HCG) concentration in serum, and patients with such germinomas are thus treated more aggressively than those with "pure" germinoma. However, the patients with germinoma and detectable HCG in CSF but not in serum ...
متن کاملSHORT REPORT Human chorionic gonadotrophin in CSF, not serum, predicts outcome in germinoma
Objectives—Some intracranial germinomas, which may contain syncytiotrophoblastic giant cells (STGCs), are associated with a mildly to moderately increased human chorionic gonadotropin (HCG) concentration in serum, and patients with such germinomas are thus treated more aggressively than those with “pure” germinoma. However, the patients with germinoma and detectable HCG in CSF but not in serum ...
متن کاملRaised serum human chorionic gonadotrophin concentrations in hyperemesis gravidarum.
Serum human chorionic gonadotrophin (HCG) concentrations were determined by radioimmunoassay with an antiserum specific to HCG beta-subunit in 42 patients with hyperemesis gravidarum and 115 women with normal pregnancies. Mean concentrations (+/- SE of mean) were higher in the women with hyperemesis gravidarum at 7-8 weeks (40.8 +/- 5.2 IU/ml v 22.1 +/- 1.4 IU/ml; P less than 0.001), 9-11 weeks...
متن کاملSerum human chorionic gonadotrophin levels in early pregnancy.
Serum hCG reference intervals for various gestational periods in normal pregnancies were determined using three commercial assays--two standardized against the WHO 2nd IS (Amersham Amerlex-M beta HCG RIA (AMX) and Abbott beta-HCG 15/15 (ABB] and one standardized against the WHO 1 IRP (Hybritech Tandem -E HCG (HYB]. Serial samples from patients with accurately determined gestational periods were...
متن کاملP-76: Stepwise Reduction of Fetal Bovine Serum Levels in Chinese Hamster OvaryCells -Expressing Human Chorionic Gonadotrophin- Culture
Background: The demand for producing recombinant therapeutic proteins by mammalian cell lines, such as Chinese hamster ovary (CHO) cells, continues to grow. Significant achievements in process optimization including development of cell culture strategies for largescale and cost-effective production have been made. Fetal bovine serum (FBS) is an often essential growth supplement and yet most cos...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1999
ISSN: 0022-3050
DOI: 10.1136/jnnp.66.5.654